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May 26, 2023
Incidence of Parkinson's disease in a large patient cohort with idiopathic smellIntroduction: Patients with idiopathic smell loss constitute an at-risk population for the development of Parkinson's disease (PD). The study aimed to [...]
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May 26, 2023
Associations of Olfaction With Longitudinal Trajectories of Brain Volumes and NeBackground and objectives: Olfactory function declines with aging, and olfactory deficits are one of the earliest features of neurodegenerative diseases, [...]
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May 19, 2023
Gut microbiota mediates the effects of curcumin on enhancing Ucp1-dependent therDue to extremely poor systemic bioavailability, the mechanism by which curcumin increases energy expenditure remains unelucidated. Accumulating evidence [...]
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May 19, 2023
5'-Adenosine monophosphate-activated protein kinase: A potential target for diseCurcumin (diferuloylmethane), a yellowish agent extracted from turmeric, is a bioactive compound known for its anti-inflammatory, antiproliferative, [...]
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May 19, 2023
Antidiabetic Properties of Curcumin I: Evidence from In Vitro Studies.Type 2 diabetes mellitus (T2DM) is a growing metabolic disease characterized by insulin resistance and hyperglycemia. Current preventative and treatment [...]
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May 19, 2023
Curcumin inhibits adipogenesis in 3T3-L1 adipocytes and angiogenesis and obesityAngiogenesis is necessary for the growth of adipose tissue. Dietary polyphenols may suppress growth of adipose tissue through their antiangiogenic [...]
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May 19, 2023
Curcumin improves adipocytes browning and mitochondrial function in 3T3-L1 cellsAccumulating evidence suggests that mitochondrial dysfunction and adipocyte differentiation promote lipid accumulation in the development of obesity and [...]
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May 19, 2023
Curcumin promotes browning of white adipose tissue in a norepinephrine-dependentBrown adipose tissue converts energy from food into heat via the mitochondrial uncoupling protein UCP1, defending against cold. In some conditions, [...]
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May 19, 2023
Autophagy and Mitochondria in Obesity and Type 2 Diabetes.Introduction: Obesity and type 2 diabetes are growing health problems worldwide. The three principal diabetogenic factors are adiposity, insulin [...]