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February 22, 2024
Oxygen radicals generated by the enzyme xanthine oxidase lyse rat pancreatic islThe endothelium-associated enzyme xanthine oxidase is known to generate reactive oxygen intermediates which may damage the surrounding tissue. We [...]
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February 22, 2024
Niacin. In Present Knowledge in Nutrition (eds J.W. Erdman, I.A. Macdonald and SThis chapter contains sections titled: Introduction Summary Niacin Structure and Nomenclature Assessment and Maintenance of Niacin [...]
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February 22, 2024
The NAD(+) precursor nicotinamide riboside enhances oxidative metabolism and proAs NAD(+) is a rate-limiting cosubstrate for the sirtuin enzymes, its modulation is emerging as a valuable tool to regulate sirtuin function and, [...]
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February 19, 2024
Potential antiviral effects of pantethine against SARS-CoV-2.SARS-CoV-2 interacts with cellular cholesterol during many stages of its replication cycle. Pantethine was reported to reduce total cholesterol levels and [...]
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February 16, 2024
Pantethine Ameliorates Recognition Impairment in a Mouse Model of Alzheimer's DiScope: As a natural dietary low-molecular-weight thiol, pantethine helps maintain brain homeostasis and function in Alzheimer's disease (AD) mice. The [...]
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February 16, 2024
Pantethine, a derivative of vitamin B5, favorably alters total, LDL and non-HDLHigh serum concentration of low-density lipoprotein cholesterol (LDL-C) is a major risk factor for coronary heart disease. The efficacy of pantethine [...]
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February 12, 2024
Effect of liquid ubiquinol supplementation on glucose, lipids and antioxidant caUbiquinone is a lipid antioxidant, and a novel liquid ubiquinol (a hydro-soluble, reduced form of coenzyme Q10) supplement was recently developed. The [...]
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February 12, 2024
Oral treatment with amitriptyline induces coenzyme Q deficiency and oxidative stAmitriptyline is a commonly prescribed tricyclic antidepressant, which has been shown to impair mitochondrial function and increase oxidative stress in a [...]
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February 12, 2024
Mitochondrial Disorder Aggravated by Metoprolol.Beta-adrenergic blocking agents or beta-blockers are a class of medications used to treat cardiac arrhythmias and systemic hypertension. In therapeutic [...]