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September 11, 2023
Omega-3 polyunsaturated fatty acid attenuates the inflammatory response by modulBackground: Microglial polarization and the subsequent neuroinflammatory response are contributing factors for traumatic brain injury (TBI)-induced [...]
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September 11, 2023
Antioxidant support to ameliorate the oxaliplatin-dependent microglial alteratioOxaliplatin is a third-generation chemotherapy drug mainly used for colorectal cancer treatment. However, it is also known to trigger neuropathy whose [...]
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September 11, 2023
2-Pentadecyl-2-Oxazoline Reduces Neuroinflammatory Environment in the MPTP ModelCurrent pharmacological management of Parkinson disease (PD) does not provide for disease modification, but addresses only symptomatic features. Here, we [...]
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September 11, 2023
Quercetin ameliorates memory impairment by inhibiting abnormal microglial activaParadoxical sleep deprivation (PSD) is prevalent in modern society, and impaired memory is one of its serious consequences. The pathogenic mechanism is [...]
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September 8, 2023
Resveratrol Inhibits NLRP3 Inflammasome-Induced Pyroptosis and miR-155 ExpressioResveratrol is a natural polyphenolic compound with a wide range of biological activities such as antioxidant, anti-carcinogenic, anti-obesity, [...]
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September 8, 2023
Mechanisms of Inhibition of Excessive Microglial Activation by Melatonin.As the innate immune cells that permanently reside in the central nervous system (CNS), microglia play an increasingly important role in maintaining brain [...]
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September 8, 2023
Rescuing mitochondria in traumatic brain injury and intracerebral hemorrhages -Mitochondria are dynamic organelles responsible for cellular energy production. Besides, regulating energy homeostasis, mitochondria are responsible for [...]
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September 8, 2023
Regulatory effects of fisetin on microglial activation.Increasing evidence suggests that inflammatory processes in the central nervous system that are mediated by microglial activation play a key role in [...]
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September 8, 2023
Inflammaging and Brain: Curcumin and Its Beneficial Potential as Regulator of MiInflammaging is a term used to describe the tight relationship between low-grade chronic inflammation and aging that occurs during physiological aging in [...]