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September 8, 2023
Alpha-lipoic acid effects on brain glial functions accompanying double-strandedDouble-stranded RNAs (dsRNA) serve as viral ligands that trigger innate immunity in astrocytes and microglial, as mediated through Toll-like receptor 3 [...]
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September 8, 2023
Physical Exercise Inhibits Inflammation and Microglial Activation.Accumulating evidence indicates that exercise can enhance brain function and attenuate neurodegeneration. Besides improving neuroplasticity by altering [...]
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September 8, 2023
Alcohol and Stress Activation of Microglia and Neurons: Brain Regional Effects.Background: Cycles of alcohol and stress are hypothesized to contribute to alcohol use disorders. How this occurs is poorly understood, although both [...]
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September 8, 2023
Biological agents and the aging brain: glial inflammation and neurotoxic signaliNeuroinflammation is a universal characteristic of brain aging and neurological disorders, irrespective of the disease state. Glial inflammation mediates [...]
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September 8, 2023
Early glycolytic reprogramming controls microglial inflammatory activation.Background: Microglial activation-mediated neuroinflammation plays an important role in the progression of neurodegenerative diseases. Inflammatory [...]
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September 8, 2023
Homocysteine exaggerates microglia activation and neuroinflammation through micrBackground: Elevated plasma homocysteine (Hcy) levels have been indicated as a strong and modifiable risk factor of ischemic stroke; the previous studies [...]
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September 8, 2023
Therapeutic targeting of microglia mediated oxidative stress after neurotrauma.Inflammation is a primary component of the central nervous system injury response. Traumatic brain and spinal cord injury are characterized by a [...]
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September 8, 2023
Systemic infections and inflammation affect chronic neurodegeneration.It is well known that systemic infections cause flare-ups of disease in individuals with asthma and rheumatoid arthritis, and that relapses in multiple [...]
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September 8, 2023
SARS-CoV-2 Infection of Microglia Elicits Proinflammatory Activation and ApoptotAccumulating evidence suggests that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection causes various neurological symptoms in [...]